BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000095015 MAP3K1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.933272 View
ENSG00000147604 RPL7 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.93312 View
ENSG00000157764 BRAF ENSG00000160007 ARHGAP35 H. sapiens SDL Slorth 0.933082 View
ENSG00000129152 MYOD1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.933053 View
ENSG00000068078 FGFR3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.932759 View
ENSG00000157764 BRAF ENSG00000186575 NF2 H. sapiens SDL Slorth 0.932363 View
ENSG00000133895 MEN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.932344 View
ENSG00000157764 BRAF ENSG00000181163 NPM1 H. sapiens SDL Slorth 0.932327 View
ENSG00000157764 BRAF ENSG00000170142 UBE2E1 H. sapiens SSL Slorth 0.932317 View
ENSG00000157764 BRAF ENSG00000170027 YWHAG H. sapiens SDL Slorth 0.932171 View
ENSG00000157764 BRAF ENSG00000169083 AR H. sapiens SSL Slorth 0.932152 View
ENSG00000157764 BRAF ENSG00000161547 SRSF2 H. sapiens SSL Slorth 0.93213 View
ENSG00000157764 BRAF ENSG00000198911 SREBF2 H. sapiens SSL Slorth 0.932081 View
ENSG00000108671 PSMD11 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.931922 View
ENSG00000080603 SRCAP ENSG00000157764 BRAF H. sapiens SSL Slorth 0.931855 View
ENSG00000114166 KAT2B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.931763 View
ENSG00000110031 LPXN ENSG00000157764 BRAF H. sapiens SDL Slorth 0.931545 View
ENSG00000099817 POLR2E ENSG00000157764 BRAF H. sapiens SDL Slorth 0.931524 View
ENSG00000113712 CSNK1A1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.931367 View
ENSG00000157764 BRAF ENSG00000172939 OXSR1 H. sapiens SDL Slorth 0.931244 View
ENSG00000114867 EIF4G1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.93124 View
ENSG00000127445 PIN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.931123 View
ENSG00000033327 GAB2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.931115 View
ENSG00000157764 BRAF ENSG00000163132 MSX1 H. sapiens SDL Slorth 0.931068 View
ENSG00000094880 CDC23 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.931066 View
ENSG00000078747 ITCH ENSG00000157764 BRAF H. sapiens SDL Slorth 0.931035 View
ENSG00000156052 GNAQ ENSG00000157764 BRAF H. sapiens SSL Slorth 0.930979 View
ENSG00000105325 FZR1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.930966 View
ENSG00000157764 BRAF ENSG00000158290 CUL4B H. sapiens SSL Slorth 0.930964 View
ENSG00000103035 PSMD7 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.930908 View
ENSG00000095015 MAP3K1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.930827 View
ENSG00000157764 BRAF ENSG00000166200 COPS2 H. sapiens SSL Slorth 0.930801 View
ENSG00000107643 MAPK8 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.930786 View
ENSG00000157764 BRAF ENSG00000188612 SUMO2 H. sapiens SSL Slorth 0.930624 View
ENSG00000157764 BRAF ENSG00000245848 CEBPA H. sapiens SSL Slorth 0.93053 View
ENSG00000157764 BRAF ENSG00000165671 NSD1 H. sapiens SDL Slorth 0.930511 View
ENSG00000157764 BRAF ENSG00000178573 MAF H. sapiens SDL Slorth 0.930367 View
ENSG00000157764 BRAF ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.930332 View
ENSG00000128245 YWHAH ENSG00000157764 BRAF H. sapiens SDL Slorth 0.930321 View
ENSG00000115694 STK25 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.930177 View