BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143878 RHOB ENSG00000157764 BRAF H. sapiens SSL Slorth 0.763723 View
ENSG00000128829 EIF2AK4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.763564 View
ENSG00000103966 EHD4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.763252 View
ENSG00000144028 SNRNP200 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.763196 View
ENSG00000157764 BRAF ENSG00000176014 TUBB6 H. sapiens SSL Slorth 0.762761 View
ENSG00000104884 ERCC2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.762621 View
ENSG00000020633 RUNX3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.762565 View
ENSG00000113595 TRIM23 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.762437 View
ENSG00000157764 BRAF ENSG00000177733 HNRNPA0 H. sapiens SSL Slorth 0.762414 View
ENSG00000118515 SGK1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.761991 View
ENSG00000157764 BRAF ENSG00000178252 WDR6 H. sapiens SSL Slorth 0.761627 View
ENSG00000090060 PAPOLA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.761519 View
ENSG00000103342 GSPT1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.76126 View
ENSG00000065135 GNAI3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.760734 View
ENSG00000105649 RAB3A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.76065 View
ENSG00000108984 MAP2K6 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.760236 View
ENSG00000140455 USP3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.760027 View
ENSG00000157764 BRAF ENSG00000198952 SMG5 H. sapiens SSL Slorth 0.759896 View
ENSG00000102900 NUP93 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.759837 View
ENSG00000078674 PCM1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.759804 View
ENSG00000123975 CKS2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.7595 View
ENSG00000070669 ASNS ENSG00000157764 BRAF H. sapiens SSL Slorth 0.759395 View
ENSG00000157764 BRAF ENSG00000173726 TOMM20 H. sapiens SSL Slorth 0.759354 View
ENSG00000143106 PSMA5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.759054 View
ENSG00000157764 BRAF ENSG00000163655 GMPS H. sapiens SSL Slorth 0.758874 View
ENSG00000133104 SPG20 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.758414 View
ENSG00000133706 LARS ENSG00000157764 BRAF H. sapiens SSL Slorth 0.758237 View
ENSG00000157764 BRAF ENSG00000196296 ATP2A1 H. sapiens SSL Slorth 0.757589 View
ENSG00000004478 FKBP4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.757542 View
ENSG00000099995 SF3A1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.757295 View
ENSG00000071794 HLTF ENSG00000157764 BRAF H. sapiens SSL Slorth 0.757102 View
ENSG00000089053 ANAPC5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.75693 View
ENSG00000148303 RPL7A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.756673 View
ENSG00000115170 ACVR1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.756639 View
ENSG00000157764 BRAF ENSG00000198431 TXNRD1 H. sapiens SSL Slorth 0.756606 View
ENSG00000076201 PTPN23 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.756588 View
ENSG00000157764 BRAF ENSG00000180353 HCLS1 H. sapiens SSL Slorth 0.756556 View
ENSG00000134243 SORT1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.756176 View
ENSG00000115806 GORASP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.756138 View
ENSG00000139083 ETV6 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.756129 View