BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000075089 ACTR6 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.943775 View
ENSG00000150753 CCT5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.94369 View
ENSG00000157764 BRAF ENSG00000172115 CYCS H. sapiens SSL Slorth 0.943636 View
ENSG00000157764 BRAF ENSG00000244687 UBE2V1 H. sapiens SDL Slorth 0.943636 View
ENSG00000110048 OSBP ENSG00000157764 BRAF H. sapiens SDL Slorth 0.943587 View
ENSG00000107581 EIF3A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.943509 View
ENSG00000157764 BRAF ENSG00000196923 PDLIM7 H. sapiens SSL Slorth 0.943477 View
ENSG00000157764 BRAF ENSG00000177189 RPS6KA3 H. sapiens SSL Slorth 0.943348 View
ENSG00000117222 RBBP5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.943281 View
ENSG00000100387 RBX1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.943279 View
ENSG00000102978 POLR2C ENSG00000157764 BRAF H. sapiens SSL Slorth 0.942868 View
ENSG00000072062 PRKACA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.942836 View
ENSG00000157764 BRAF ENSG00000240771 ARHGEF25 H. sapiens SDL Slorth 0.942608 View
ENSG00000154582 TCEB1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.942603 View
ENSG00000062650 WAPL ENSG00000157764 BRAF H. sapiens SSL Slorth 0.942597 View
ENSG00000006451 RALA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.942444 View
ENSG00000157764 BRAF ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.942416 View
ENSG00000023445 BIRC3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.9424 View
ENSG00000041357 PSMA4 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.942321 View
ENSG00000145604 SKP2 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.942257 View
ENSG00000157764 BRAF ENSG00000172071 EIF2AK3 H. sapiens SDL Slorth 0.942249 View
ENSG00000067606 PRKCZ ENSG00000157764 BRAF H. sapiens SSL Slorth 0.942063 View
ENSG00000143190 POU2F1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.941941 View
ENSG00000080824 HSP90AA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.941883 View
ENSG00000154229 PRKCA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.941785 View
ENSG00000157764 BRAF ENSG00000169714 CNBP H. sapiens SDL Slorth 0.941773 View
ENSG00000157764 BRAF ENSG00000166913 YWHAB H. sapiens SDL Slorth 0.941546 View
ENSG00000157764 BRAF ENSG00000165731 RET H. sapiens SDL Slorth 0.941461 View
ENSG00000080503 SMARCA2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.941398 View
ENSG00000117676 RPS6KA1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.941383 View
ENSG00000157764 BRAF ENSG00000164736 SOX17 H. sapiens SDL Slorth 0.941286 View
ENSG00000157764 BRAF ENSG00000161940 BCL6B H. sapiens SDL Slorth 0.94125 View
ENSG00000061938 TNK2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.941229 View
ENSG00000149923 PPP4C ENSG00000157764 BRAF H. sapiens SSL Slorth 0.941128 View
ENSG00000099804 CDC34 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.940962 View
ENSG00000157764 BRAF ENSG00000160803 UBQLN4 H. sapiens SSL Slorth 0.94085 View
ENSG00000130177 CDC16 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.940719 View
ENSG00000157764 BRAF ENSG00000188906 LRRK2 H. sapiens SDL Slorth 0.940477 View
ENSG00000157764 BRAF ENSG00000168646 AXIN2 H. sapiens SDL Slorth 0.940462 View
ENSG00000157764 BRAF ENSG00000160271 RALGDS H. sapiens SDL Slorth 0.940091 View