BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000135503 ACVR1B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.916812 View
ENSG00000126785 RHOJ ENSG00000157764 BRAF H. sapiens SDL Slorth 0.916645 View
ENSG00000119718 EIF2B2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.916593 View
ENSG00000112679 DUSP22 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.916444 View
ENSG00000157764 BRAF ENSG00000198742 SMURF1 H. sapiens SDL Slorth 0.916203 View
ENSG00000105647 PIK3R2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.916199 View
ENSG00000142864 SERBP1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.916151 View
ENSG00000109320 NFKB1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.916126 View
ENSG00000157764 BRAF ENSG00000169372 CRADD H. sapiens SDL Slorth 0.916093 View
ENSG00000157601 MX1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.915984 View
ENSG00000100028 SNRPD3 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.915916 View
ENSG00000157764 BRAF ENSG00000213672 NCKIPSD H. sapiens SDL Slorth 0.915728 View
ENSG00000100142 POLR2F ENSG00000157764 BRAF H. sapiens SSL Slorth 0.915532 View
ENSG00000102054 RBBP7 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.915479 View
ENSG00000157764 BRAF ENSG00000163485 ADORA1 H. sapiens SDL Slorth 0.915408 View
ENSG00000153147 SMARCA5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.91534 View
ENSG00000140262 TCF12 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.915258 View
ENSG00000133794 ARNTL ENSG00000157764 BRAF H. sapiens SSL Slorth 0.915256 View
ENSG00000115904 SOS1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.915196 View
ENSG00000119487 MAPKAP1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.915147 View
ENSG00000121022 COPS5 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.915031 View
ENSG00000069869 NEDD4 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.915026 View
ENSG00000039068 CDH1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.914977 View
ENSG00000147573 TRIM55 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.914524 View
ENSG00000155959 VBP1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.914512 View
ENSG00000137845 ADAM10 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.914305 View
ENSG00000114503 NCBP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.913988 View
ENSG00000136100 VPS36 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.913896 View
ENSG00000157764 BRAF ENSG00000175203 DCTN2 H. sapiens SSL Slorth 0.913864 View
ENSG00000061918 GUCY1B3 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.913853 View
ENSG00000137073 UBAP2 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.913739 View
ENSG00000101442 ACTR5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.913523 View
ENSG00000157764 BRAF ENSG00000185236 RAB11B H. sapiens SDL Slorth 0.913488 View
ENSG00000100029 PES1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.913275 View
ENSG00000152822 GRM1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.913233 View
ENSG00000157764 BRAF ENSG00000170144 HNRNPA3 H. sapiens SSL Slorth 0.913227 View
ENSG00000134480 CCNH ENSG00000157764 BRAF H. sapiens SSL Slorth 0.913211 View
ENSG00000089154 GCN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.913203 View
ENSG00000079277 MKNK1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.912976 View
ENSG00000100347 SAMM50 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.912819 View