BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000055130 CUL1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.93012 View
ENSG00000157764 BRAF ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.92978 View
ENSG00000050748 MAPK9 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.92976 View
ENSG00000106245 BUD31 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.929662 View
ENSG00000114573 ATP6V1A ENSG00000157764 BRAF H. sapiens SDL Slorth 0.929485 View
ENSG00000123358 NR4A1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.929328 View
ENSG00000096717 SIRT1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.929308 View
ENSG00000157764 BRAF ENSG00000163938 GNL3 H. sapiens SSL Slorth 0.929118 View
ENSG00000113722 CDX1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.929101 View
ENSG00000100906 NFKBIA ENSG00000157764 BRAF H. sapiens SDL Slorth 0.929053 View
ENSG00000122257 RBBP6 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.928976 View
ENSG00000130811 EIF3G ENSG00000157764 BRAF H. sapiens SSL Slorth 0.928854 View
ENSG00000064012 CASP8 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.928847 View
ENSG00000157764 BRAF ENSG00000169696 ASPSCR1 H. sapiens SDL Slorth 0.928824 View
ENSG00000156970 BUB1B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.928604 View
ENSG00000107404 DVL1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.928387 View
ENSG00000103479 RBL2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.928281 View
ENSG00000100554 ATP6V1D ENSG00000157764 BRAF H. sapiens SSL Slorth 0.92824 View
ENSG00000157764 BRAF ENSG00000173039 RELA H. sapiens SDL Slorth 0.928199 View
ENSG00000085840 ORC1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.928114 View
ENSG00000092201 SUPT16H ENSG00000157764 BRAF H. sapiens SSL Slorth 0.927702 View
ENSG00000120837 NFYB ENSG00000157764 BRAF H. sapiens SSL Slorth 0.927664 View
ENSG00000157764 BRAF ENSG00000163513 TGFBR2 H. sapiens SSL Slorth 0.927616 View
ENSG00000072163 LIMS2 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.92751 View
ENSG00000157764 BRAF ENSG00000158402 CDC25C H. sapiens SDL Slorth 0.927479 View
ENSG00000001626 CFTR ENSG00000157764 BRAF H. sapiens SDL Slorth 0.927407 View
ENSG00000139197 PEX5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.927179 View
ENSG00000157764 BRAF ENSG00000161956 SENP3 H. sapiens SSL Slorth 0.92694 View
ENSG00000157764 BRAF ENSG00000198825 INPP5F H. sapiens SDL Slorth 0.926872 View
ENSG00000157764 BRAF ENSG00000185104 FAF1 H. sapiens SSL Slorth 0.926856 View
ENSG00000157764 BRAF ENSG00000204435 CSNK2B H. sapiens SDL Slorth 0.926737 View
ENSG00000138814 PPP3CA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.926731 View
ENSG00000157764 BRAF ENSG00000173110 HSPA6 H. sapiens SSL Slorth 0.926722 View
ENSG00000157764 BRAF ENSG00000169139 UBE2V2 H. sapiens SDL Slorth 0.926478 View
ENSG00000131759 RARA ENSG00000157764 BRAF H. sapiens SDL Slorth 0.926285 View
ENSG00000136527 TRA2B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.926277 View
ENSG00000141367 CLTC ENSG00000157764 BRAF H. sapiens SDL Slorth 0.926253 View
ENSG00000135341 MAP3K7 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.926203 View
ENSG00000007168 PAFAH1B1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.926088 View
ENSG00000157764 BRAF ENSG00000179262 RAD23A H. sapiens SSL Slorth 0.926085 View