BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000003400 CASP10 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.925903 View
ENSG00000023445 BIRC3 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.925785 View
ENSG00000157764 BRAF ENSG00000164362 TERT H. sapiens SDL Slorth 0.925778 View
ENSG00000068305 MEF2A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.925682 View
ENSG00000094804 CDC6 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.925542 View
ENSG00000157764 BRAF ENSG00000244405 ETV5 H. sapiens SDL Slorth 0.925476 View
ENSG00000157764 BRAF ENSG00000166851 PLK1 H. sapiens SDL Slorth 0.925392 View
ENSG00000090020 SLC9A1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.925381 View
ENSG00000157764 BRAF ENSG00000172531 PPP1CA H. sapiens SDL Slorth 0.925265 View
ENSG00000157764 BRAF ENSG00000221829 FANCG H. sapiens SDL Slorth 0.925193 View
ENSG00000157764 BRAF ENSG00000196628 TCF4 H. sapiens SSL Slorth 0.925095 View
ENSG00000071242 RPS6KA2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.924761 View
ENSG00000157764 BRAF ENSG00000168556 ING2 H. sapiens SSL Slorth 0.924609 View
ENSG00000047249 ATP6V1H ENSG00000157764 BRAF H. sapiens SSL Slorth 0.924562 View
ENSG00000101412 E2F1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.924512 View
ENSG00000153250 RBMS1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.924435 View
ENSG00000157764 BRAF ENSG00000198873 GRK5 H. sapiens SDL Slorth 0.92443 View
ENSG00000137834 SMAD6 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.924168 View
ENSG00000084774 CAD ENSG00000157764 BRAF H. sapiens SDL Slorth 0.923862 View
ENSG00000079387 SENP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.923695 View
ENSG00000157764 BRAF ENSG00000170035 UBE2E3 H. sapiens SSL Slorth 0.923567 View
ENSG00000157764 BRAF ENSG00000168918 INPP5D H. sapiens SSL Slorth 0.923377 View
ENSG00000111859 NEDD9 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.923165 View
ENSG00000068024 HDAC4 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.923039 View
ENSG00000118503 TNFAIP3 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.923033 View
ENSG00000157764 BRAF ENSG00000160789 LMNA H. sapiens SSL Slorth 0.922934 View
ENSG00000116459 ATP5F1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.922883 View
ENSG00000157764 BRAF ENSG00000241837 ATP5O H. sapiens SSL Slorth 0.922786 View
ENSG00000114302 PRKAR2A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.922722 View
ENSG00000157764 BRAF ENSG00000161960 EIF4A1 H. sapiens SSL Slorth 0.92256 View
ENSG00000157764 BRAF ENSG00000196305 IARS H. sapiens SSL Slorth 0.922522 View
ENSG00000157764 BRAF ENSG00000185359 HGS H. sapiens SDL Slorth 0.922178 View
ENSG00000101843 PSMD10 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.922043 View
ENSG00000117614 SYF2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.92198 View
ENSG00000157764 BRAF ENSG00000203879 GDI1 H. sapiens SDL Slorth 0.921957 View
ENSG00000116251 RPL22 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.921913 View
ENSG00000141367 CLTC ENSG00000157764 BRAF H. sapiens SSL Slorth 0.921786 View
ENSG00000049618 ARID1B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.921784 View
ENSG00000157764 BRAF ENSG00000175390 EIF3F H. sapiens SSL Slorth 0.921722 View
ENSG00000157764 BRAF ENSG00000213585 VDAC1 H. sapiens SSL Slorth 0.921667 View