BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000100028 SNRPD3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.863455 View
ENSG00000157764 BRAF ENSG00000184557 SOCS3 H. sapiens SSL Slorth 0.863288 View
ENSG00000090020 SLC9A1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.863081 View
ENSG00000157764 BRAF ENSG00000163840 DTX3L H. sapiens SSL Slorth 0.86294 View
ENSG00000157764 BRAF ENSG00000168439 STIP1 H. sapiens SSL Slorth 0.862788 View
ENSG00000157764 BRAF ENSG00000168090 COPS6 H. sapiens SSL Slorth 0.862762 View
ENSG00000136273 HUS1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.862512 View
ENSG00000128052 KDR ENSG00000157764 BRAF H. sapiens SSL Slorth 0.862293 View
ENSG00000010256 UQCRC1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.862138 View
ENSG00000280548 FBL ENSG00000157764 BRAF H. sapiens SSL Slorth 0.861988 View
ENSG00000157764 BRAF ENSG00000169855 ROBO1 H. sapiens SSL Slorth 0.861694 View
ENSG00000107651 SEC23IP ENSG00000157764 BRAF H. sapiens SSL Slorth 0.861599 View
ENSG00000157764 BRAF ENSG00000162909 CAPN2 H. sapiens SSL Slorth 0.861475 View
ENSG00000096401 CDC5L ENSG00000157764 BRAF H. sapiens SSL Slorth 0.861181 View
ENSG00000110955 ATP5B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.860269 View
ENSG00000008128 CDK11A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.859838 View
ENSG00000157764 BRAF ENSG00000172845 SP3 H. sapiens SSL Slorth 0.859663 View
ENSG00000064995 TAF11 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.85924 View
ENSG00000078142 PIK3C3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.859214 View
ENSG00000130332 LSM7 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.858803 View
ENSG00000157764 BRAF ENSG00000184432 COPB2 H. sapiens SSL Slorth 0.858517 View
ENSG00000157764 BRAF ENSG00000168118 RAB4A H. sapiens SSL Slorth 0.858465 View
ENSG00000104408 EIF3E ENSG00000157764 BRAF H. sapiens SSL Slorth 0.857997 View
ENSG00000147162 OGT ENSG00000157764 BRAF H. sapiens SSL Slorth 0.85782 View
ENSG00000072274 TFRC ENSG00000157764 BRAF H. sapiens SSL Slorth 0.857762 View
ENSG00000148737 TCF7L2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.857571 View
ENSG00000157764 BRAF ENSG00000178921 PFAS H. sapiens SSL Slorth 0.857562 View
ENSG00000134352 IL6ST ENSG00000157764 BRAF H. sapiens SSL Slorth 0.857166 View
ENSG00000135766 EGLN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.856436 View
ENSG00000157764 BRAF ENSG00000171720 HDAC3 H. sapiens SSL Slorth 0.856107 View
ENSG00000138081 FBXO11 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.855972 View
ENSG00000157764 BRAF ENSG00000168872 DDX19A H. sapiens SSL Slorth 0.855626 View
ENSG00000149792 MRPL49 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.855457 View
ENSG00000070018 LRP6 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.85539 View
ENSG00000115816 CEBPZ ENSG00000157764 BRAF H. sapiens SSL Slorth 0.855069 View
ENSG00000071127 WDR1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.854831 View
ENSG00000078304 PPP2R5C ENSG00000157764 BRAF H. sapiens SSL Slorth 0.854508 View
ENSG00000104907 TRMT1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.854225 View
ENSG00000099940 SNAP29 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.854048 View
ENSG00000116288 PARK7 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.854019 View