BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000089289 IGBP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.889487 View
ENSG00000123349 PFDN5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.889429 View
ENSG00000108094 CUL2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.889091 View
ENSG00000129083 COPB1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.888889 View
ENSG00000138385 SSB ENSG00000157764 BRAF H. sapiens SSL Slorth 0.888818 View
ENSG00000134070 IRAK2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.888706 View
ENSG00000157764 BRAF ENSG00000184787 UBE2G2 H. sapiens SSL Slorth 0.888652 View
ENSG00000076984 MAP2K7 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.888525 View
ENSG00000116604 MEF2D ENSG00000157764 BRAF H. sapiens SSL Slorth 0.887994 View
ENSG00000102981 PARD6A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.887888 View
ENSG00000109339 MAPK10 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.88762 View
ENSG00000114126 TFDP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.887565 View
ENSG00000157764 BRAF ENSG00000173757 STAT5B H. sapiens SSL Slorth 0.887274 View
ENSG00000157764 BRAF ENSG00000165916 PSMC3 H. sapiens SSL Slorth 0.887127 View
ENSG00000157764 BRAF ENSG00000197943 PLCG2 H. sapiens SSL Slorth 0.887055 View
ENSG00000105639 JAK3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.886877 View
ENSG00000115129 TP53I3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.886599 View
ENSG00000069329 VPS35 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.886498 View
ENSG00000157764 BRAF ENSG00000175054 ATR H. sapiens SSL Slorth 0.886474 View
ENSG00000088832 FKBP1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.886244 View
ENSG00000057657 PRDM1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.885742 View
ENSG00000034152 MAP2K3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.885704 View
ENSG00000157764 BRAF ENSG00000166925 TSC22D4 H. sapiens SSL Slorth 0.885703 View
ENSG00000131023 LATS1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.885504 View
ENSG00000101871 MID1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.885455 View
ENSG00000155974 GRIP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.885432 View
ENSG00000157764 BRAF ENSG00000159023 EPB41 H. sapiens SSL Slorth 0.885345 View
ENSG00000131475 VPS25 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.885235 View
ENSG00000033800 PIAS1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.88519 View
ENSG00000127824 TUBA4A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.884704 View
ENSG00000157764 BRAF ENSG00000181449 SOX2 H. sapiens SSL Slorth 0.884663 View
ENSG00000157764 BRAF ENSG00000184260 HIST2H2AC H. sapiens SSL Slorth 0.88463 View
ENSG00000157764 BRAF ENSG00000166888 STAT6 H. sapiens SSL Slorth 0.884342 View
ENSG00000124222 STX16 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.884242 View
ENSG00000157764 BRAF ENSG00000161203 AP2M1 H. sapiens SSL Slorth 0.884107 View
ENSG00000049759 NEDD4L ENSG00000157764 BRAF H. sapiens SSL Slorth 0.883705 View
ENSG00000102038 SMARCA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.883402 View
ENSG00000157764 BRAF ENSG00000168066 SF1 H. sapiens SSL Slorth 0.883402 View
ENSG00000157764 BRAF ENSG00000164134 NAA15 H. sapiens SSL Slorth 0.883191 View
ENSG00000157764 BRAF ENSG00000159251 ACTC1 H. sapiens SSL Slorth 0.883117 View