BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000156304 SCAF4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.826174 View
ENSG00000157764 BRAF ENSG00000183337 BCOR H. sapiens SSL Slorth 0.825934 View
ENSG00000106105 GARS ENSG00000157764 BRAF H. sapiens SSL Slorth 0.825727 View
ENSG00000157764 BRAF ENSG00000182979 MTA1 H. sapiens SSL Slorth 0.825571 View
ENSG00000157764 BRAF ENSG00000185787 MORF4L1 H. sapiens SSL Slorth 0.82476 View
ENSG00000101003 GINS1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.82473 View
ENSG00000157764 BRAF ENSG00000174672 BRSK2 H. sapiens SSL Slorth 0.824697 View
ENSG00000130479 MAP1S ENSG00000157764 BRAF H. sapiens SSL Slorth 0.824527 View
ENSG00000105401 CDC37 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.824495 View
ENSG00000157764 BRAF ENSG00000158711 ELK4 H. sapiens SSL Slorth 0.824445 View
ENSG00000083799 CYLD ENSG00000157764 BRAF H. sapiens SSL Slorth 0.82444 View
ENSG00000148688 RPP30 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.8244 View
ENSG00000100697 DICER1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.823921 View
ENSG00000128578 STRIP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.823895 View
ENSG00000157764 BRAF ENSG00000164690 SHH H. sapiens SSL Slorth 0.823883 View
ENSG00000157764 BRAF ENSG00000176248 ANAPC2 H. sapiens SSL Slorth 0.823691 View
ENSG00000157764 BRAF ENSG00000198286 CARD11 H. sapiens SSL Slorth 0.823524 View
ENSG00000134684 YARS ENSG00000157764 BRAF H. sapiens SSL Slorth 0.823335 View
ENSG00000153107 ANAPC1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.823278 View
ENSG00000119912 IDE ENSG00000157764 BRAF H. sapiens SSL Slorth 0.823215 View
ENSG00000157764 BRAF ENSG00000187266 EPOR H. sapiens SSL Slorth 0.822646 View
ENSG00000157764 BRAF ENSG00000158092 NCK1 H. sapiens SSL Slorth 0.822459 View
ENSG00000108883 EFTUD2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.821229 View
ENSG00000001630 CYP51A1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.820861 View
ENSG00000157764 BRAF ENSG00000165637 VDAC2 H. sapiens SSL Slorth 0.820586 View
ENSG00000157764 BRAF ENSG00000239857 GET4 H. sapiens SSL Slorth 0.820031 View
ENSG00000077150 NFKB2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.819789 View
ENSG00000157764 BRAF ENSG00000203879 GDI1 H. sapiens SSL Slorth 0.819479 View
ENSG00000108561 C1QBP ENSG00000157764 BRAF H. sapiens SSL Slorth 0.819359 View
ENSG00000138448 ITGAV ENSG00000157764 BRAF H. sapiens SSL Slorth 0.818671 View
ENSG00000043093 DCUN1D1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.818394 View
ENSG00000157764 BRAF ENSG00000169189 NSMCE1 H. sapiens SSL Slorth 0.818225 View
ENSG00000105248 CCDC94 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.818199 View
ENSG00000157764 BRAF ENSG00000183955 KMT5A H. sapiens SSL Slorth 0.817946 View
ENSG00000157764 BRAF ENSG00000163029 SMC6 H. sapiens SSL Slorth 0.817937 View
ENSG00000157764 BRAF ENSG00000187840 EIF4EBP1 H. sapiens SSL Slorth 0.817856 View
ENSG00000109189 USP46 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.817719 View
ENSG00000145216 FIP1L1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.817589 View
ENSG00000157764 BRAF ENSG00000196924 FLNA H. sapiens SSL Slorth 0.817227 View
ENSG00000157764 BRAF ENSG00000168421 RHOH H. sapiens SSL Slorth 0.816826 View