BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000088833 NSFL1C ENSG00000157764 BRAF H. sapiens SSL Slorth 0.876673 View
ENSG00000157456 CCNB2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.876551 View
ENSG00000112335 SNX3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.876332 View
ENSG00000157764 BRAF ENSG00000159377 PSMB4 H. sapiens SSL Slorth 0.875939 View
ENSG00000144744 UBA3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.875679 View
ENSG00000100934 SEC23A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.875675 View
ENSG00000105258 POLR2I ENSG00000157764 BRAF H. sapiens SSL Slorth 0.875587 View
ENSG00000111361 EIF2B1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.875544 View
ENSG00000157764 BRAF ENSG00000173020 GRK2 H. sapiens SSL Slorth 0.875403 View
ENSG00000126351 THRA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.875266 View
ENSG00000108510 MED13 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.875173 View
ENSG00000157764 BRAF ENSG00000184009 ACTG1 H. sapiens SSL Slorth 0.875067 View
ENSG00000076604 TRAF4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.875034 View
ENSG00000140807 NKD1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.874715 View
ENSG00000136152 COG3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.874703 View
ENSG00000139613 SMARCC2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.874638 View
ENSG00000111229 ARPC3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.874612 View
ENSG00000095139 ARCN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.874372 View
ENSG00000086598 TMED2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.87406 View
ENSG00000105221 AKT2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.873986 View
ENSG00000125971 DYNLRB1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.873892 View
ENSG00000120656 TAF12 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.8736 View
ENSG00000070367 EXOC5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.873598 View
ENSG00000134014 ELP3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.873574 View
ENSG00000065054 SLC9A3R2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.873561 View
ENSG00000157764 BRAF ENSG00000161057 PSMC2 H. sapiens SSL Slorth 0.873331 View
ENSG00000155511 GRIA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.873272 View
ENSG00000157764 BRAF ENSG00000176884 GRIN1 H. sapiens SSL Slorth 0.873193 View
ENSG00000108106 UBE2S ENSG00000157764 BRAF H. sapiens SSL Slorth 0.872754 View
ENSG00000104980 TIMM44 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.872535 View
ENSG00000118058 KMT2A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.872458 View
ENSG00000157764 BRAF ENSG00000184481 FOXO4 H. sapiens SSL Slorth 0.872407 View
ENSG00000014138 POLA2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.872359 View
ENSG00000138758 SEPT11 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.87231 View
ENSG00000157764 BRAF ENSG00000205726 ITSN1 H. sapiens SSL Slorth 0.872117 View
ENSG00000077782 FGFR1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.872083 View
ENSG00000140941 MAP1LC3B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.871888 View
ENSG00000096746 HNRNPH3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.871848 View
ENSG00000081189 MEF2C ENSG00000157764 BRAF H. sapiens SSL Slorth 0.871825 View
ENSG00000092820 EZR ENSG00000157764 BRAF H. sapiens SSL Slorth 0.871805 View