BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000090376 IRAK3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.871664 View
ENSG00000145907 G3BP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.871338 View
ENSG00000140682 TGFB1I1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.87124 View
ENSG00000118971 CCND2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.871114 View
ENSG00000157764 BRAF ENSG00000248333 CDK11B H. sapiens SSL Slorth 0.871044 View
ENSG00000132356 PRKAA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.870945 View
ENSG00000103549 RNF40 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.870712 View
ENSG00000004487 KDM1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.870626 View
ENSG00000157764 BRAF ENSG00000183431 SF3A3 H. sapiens SSL Slorth 0.870337 View
ENSG00000124422 USP22 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.870256 View
ENSG00000060971 ACAA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.870019 View
ENSG00000157764 BRAF ENSG00000197157 SND1 H. sapiens SSL Slorth 0.869842 View
ENSG00000157764 BRAF ENSG00000197451 HNRNPAB H. sapiens SSL Slorth 0.86978 View
ENSG00000057608 GDI2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.869448 View
ENSG00000083168 KAT6A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.869345 View
ENSG00000141867 BRD4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.869018 View
ENSG00000157764 BRAF ENSG00000198836 OPA1 H. sapiens SSL Slorth 0.868929 View
ENSG00000157764 BRAF ENSG00000196866 HIST1H2AD H. sapiens SSL Slorth 0.868775 View
ENSG00000157764 BRAF ENSG00000176890 TYMS H. sapiens SSL Slorth 0.868483 View
ENSG00000149480 MTA2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.868264 View
ENSG00000157764 BRAF ENSG00000162236 STX5 H. sapiens SSL Slorth 0.868207 View
ENSG00000157764 BRAF ENSG00000238134 EHMT2 H. sapiens SSL Slorth 0.868001 View
ENSG00000104852 SNRNP70 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.867734 View
ENSG00000104517 UBR5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.867725 View
ENSG00000126581 BECN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.86762 View
ENSG00000072310 SREBF1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.867315 View
ENSG00000157764 BRAF ENSG00000164104 HMGB2 H. sapiens SSL Slorth 0.867124 View
ENSG00000042088 TDP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.866933 View
ENSG00000157764 BRAF ENSG00000159459 UBR1 H. sapiens SSL Slorth 0.866846 View
ENSG00000157764 BRAF ENSG00000169564 PCBP1 H. sapiens SSL Slorth 0.866667 View
ENSG00000157764 BRAF ENSG00000165699 TSC1 H. sapiens SSL Slorth 0.866471 View
ENSG00000053372 MRTO4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.866358 View
ENSG00000152234 ATP5A1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.866304 View
ENSG00000113312 TTC1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.865809 View
ENSG00000077254 USP33 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.865213 View
ENSG00000157764 BRAF ENSG00000170485 NPAS2 H. sapiens SSL Slorth 0.865068 View
ENSG00000103363 TCEB2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.864999 View
ENSG00000133226 SRRM1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.864574 View
ENSG00000131747 TOP2A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.864393 View
ENSG00000157764 BRAF ENSG00000185338 SOCS1 H. sapiens SSL Slorth 0.863624 View