ARNTL - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARNTL	ENSG00000133794	No diseases in record	No drugs in record	transcription regulatory region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding core promoter binding DNA binding protein binding aryl hydrocarbon receptor binding sequence-specific DNA binding protein dimerization activity Hsp90 protein binding repressing transcription factor binding E-box binding	hlh-34 (C. elegans) cyc (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)