BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000157764 BRAF ENSG00000182255 KCNA4 H. sapiens SDL Slorth 0.907916 View
ENSG00000157764 BRAF ENSG00000185591 SP1 H. sapiens SDL Slorth 0.907893 View
ENSG00000133703 KRAS ENSG00000157764 BRAF H. sapiens SDL Slorth 0.907801 View
ENSG00000101199 ARFGAP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.907771 View
ENSG00000101665 SMAD7 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.907741 View
ENSG00000105173 CCNE1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.907725 View
ENSG00000118898 PPL ENSG00000157764 BRAF H. sapiens SDL Slorth 0.907532 View
ENSG00000157764 BRAF ENSG00000174791 RIN1 H. sapiens SSL Slorth 0.907528 View
ENSG00000157764 BRAF ENSG00000179218 CALR H. sapiens SSL Slorth 0.907401 View
ENSG00000127445 PIN1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.907344 View
ENSG00000157764 BRAF ENSG00000182606 TRAK1 H. sapiens SDL Slorth 0.907342 View
ENSG00000151090 THRB ENSG00000157764 BRAF H. sapiens SSL Slorth 0.907298 View
ENSG00000083520 DIS3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.907295 View
ENSG00000157764 BRAF ENSG00000160208 RRP1B H. sapiens SSL Slorth 0.90723 View
ENSG00000138668 HNRNPD ENSG00000157764 BRAF H. sapiens SSL Slorth 0.907091 View
ENSG00000102755 FLT1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.906889 View
ENSG00000107581 EIF3A ENSG00000157764 BRAF H. sapiens SDL Slorth 0.906884 View
ENSG00000157764 BRAF ENSG00000198176 TFDP1 H. sapiens SSL Slorth 0.906806 View
ENSG00000157764 BRAF ENSG00000183765 CHEK2 H. sapiens SSL Slorth 0.906782 View
ENSG00000157764 BRAF ENSG00000173801 JUP H. sapiens SDL Slorth 0.906766 View
ENSG00000148677 ANKRD1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.906682 View
ENSG00000157404 KIT ENSG00000157764 BRAF H. sapiens SSL Slorth 0.906558 View
ENSG00000028839 TBPL1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.906341 View
ENSG00000094916 CBX5 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.906305 View
ENSG00000157764 BRAF ENSG00000196961 AP2A1 H. sapiens SSL Slorth 0.906281 View
ENSG00000106070 GRB10 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.90625 View
ENSG00000129245 FXR2 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.906212 View
ENSG00000076555 ACACB ENSG00000157764 BRAF H. sapiens SSL Slorth 0.90602 View
ENSG00000079156 OSBPL6 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.905904 View
ENSG00000147010 SH3KBP1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.905811 View
ENSG00000157764 BRAF ENSG00000189403 HMGB1 H. sapiens SSL Slorth 0.905746 View
ENSG00000010292 NCAPD2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.905736 View
ENSG00000094916 CBX5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.905736 View
ENSG00000157764 BRAF ENSG00000167461 RAB8A H. sapiens SSL Slorth 0.905668 View
ENSG00000104738 MCM4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.905653 View
ENSG00000067606 PRKCZ ENSG00000157764 BRAF H. sapiens SDL Slorth 0.905577 View
ENSG00000144566 RAB5A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.905555 View
ENSG00000112237 CCNC ENSG00000157764 BRAF H. sapiens SSL Slorth 0.90548 View
ENSG00000151461 UPF2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.90539 View
ENSG00000111602 TIMELESS ENSG00000157764 BRAF H. sapiens SSL Slorth 0.905246 View