ITGAV - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ITGAV	ENSG00000138448	large intestine carcinoma	No drugs in record	virus receptor activity fibronectin binding protease binding voltage-gated calcium channel activity protein binding coreceptor activity metal ion binding transforming growth factor beta binding extracellular matrix binding extracellular matrix protein binding opsonin binding protein kinase C binding fibroblast growth factor binding C-X3-C chemokine binding insulin-like growth factor I binding neuregulin binding	pat-2 (C. elegans) if (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)