BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000134909 ARHGAP32 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.796058 View
ENSG00000092964 DPYSL2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.795396 View
ENSG00000142453 CARM1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.794876 View
ENSG00000133216 EPHB2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.794475 View
ENSG00000157764 BRAF ENSG00000182944 EWSR1 H. sapiens SSL Slorth 0.794296 View
ENSG00000157764 BRAF ENSG00000197837 HIST4H4 H. sapiens SSL Slorth 0.794197 View
ENSG00000157764 BRAF ENSG00000172725 CORO1B H. sapiens SSL Slorth 0.794022 View
ENSG00000023287 RB1CC1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.79388 View
ENSG00000157764 BRAF ENSG00000196262 PPIA H. sapiens SSL Slorth 0.793693 View
ENSG00000157764 BRAF ENSG00000178573 MAF H. sapiens SSL Slorth 0.793372 View
ENSG00000115325 DOK1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.792346 View
ENSG00000157764 BRAF ENSG00000167216 KATNAL2 H. sapiens SSL Slorth 0.792157 View
ENSG00000143761 ARF1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.792146 View
ENSG00000157764 BRAF ENSG00000163918 RFC4 H. sapiens SSL Slorth 0.791848 View
ENSG00000157764 BRAF ENSG00000179335 CLK3 H. sapiens SSL Slorth 0.791703 View
ENSG00000007392 LUC7L ENSG00000157764 BRAF H. sapiens SSL Slorth 0.791392 View
ENSG00000157764 BRAF ENSG00000184575 XPOT H. sapiens SSL Slorth 0.791337 View
ENSG00000157764 BRAF ENSG00000182621 PLCB1 H. sapiens SSL Slorth 0.791268 View
ENSG00000157764 BRAF ENSG00000162924 REL H. sapiens SSL Slorth 0.791205 View
ENSG00000157764 BRAF ENSG00000176749 CDK5R1 H. sapiens SSL Slorth 0.79116 View
ENSG00000064703 DDX20 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.790889 View
ENSG00000133026 MYH10 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.790713 View
ENSG00000157764 BRAF ENSG00000166803 KIAA0101 H. sapiens SSL Slorth 0.79068 View
ENSG00000157764 BRAF ENSG00000204301 NOTCH4 H. sapiens SSL Slorth 0.790558 View
ENSG00000049541 RFC2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.790472 View
ENSG00000157764 BRAF ENSG00000178896 EXOSC4 H. sapiens SSL Slorth 0.790312 View
ENSG00000020922 MRE11 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.790025 View
ENSG00000065665 SEC61A2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.789996 View
ENSG00000101310 SEC23B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.789828 View
ENSG00000157764 BRAF ENSG00000213465 ARL2 H. sapiens SSL Slorth 0.78971 View
ENSG00000112578 BYSL ENSG00000157764 BRAF H. sapiens SSL Slorth 0.789012 View
ENSG00000157764 BRAF ENSG00000196586 MYO6 H. sapiens SSL Slorth 0.788525 View
ENSG00000107295 SH3GL2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.788412 View
ENSG00000134899 ERCC5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.7884 View
ENSG00000085224 ATRX ENSG00000157764 BRAF H. sapiens SSL Slorth 0.788163 View
ENSG00000157764 BRAF ENSG00000182759 MAFA H. sapiens SSL Slorth 0.788115 View
ENSG00000157764 BRAF ENSG00000196911 KPNA5 H. sapiens SSL Slorth 0.787953 View
ENSG00000119689 DLST ENSG00000157764 BRAF H. sapiens SSL Slorth 0.787717 View
ENSG00000111641 NOP2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.787668 View
ENSG00000157764 BRAF ENSG00000166747 AP1G1 H. sapiens SSL Slorth 0.787545 View