JAK1

ENSG00000162434 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005131 growth hormone receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019903 protein phosphatase binding
GO:0031625 ubiquitin protein ligase binding
GO:0031730 CCR5 chemokine receptor binding
GO:0046872 metal ion binding

Drugs

Drug name Description
RUXOLITINIB Tyrosine-protein kinase JAK2 inhibitor
TOFACITINIB Janus Kinase (JAK) inhibitor

Diseases

Disease Name
ALL

Orthologs

Gene Organism
hop D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000162434 JAK1 ENSG00000165731 RET H. sapiens SSL Slorth 0.880824 View
ENSG00000013503 POLR3B ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.880518 View
ENSG00000142655 PEX14 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.880421 View
ENSG00000103363 TCEB2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.880322 View
ENSG00000110713 NUP98 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.880243 View
ENSG00000065427 KARS ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.879893 View
ENSG00000113722 CDX1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.879182 View
ENSG00000162434 JAK1 ENSG00000164362 TERT H. sapiens SSL Slorth 0.879142 View
ENSG00000105011 ASF1B ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.879 View
ENSG00000147162 OGT ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.878935 View
ENSG00000101367 MAPRE1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.878925 View
ENSG00000070756 PABPC1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.878814 View
ENSG00000131023 LATS1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.878374 View
ENSG00000154767 XPC ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.878342 View
ENSG00000162434 JAK1 ENSG00000186716 BCR H. sapiens SSL Slorth 0.878216 View
ENSG00000137076 TLN1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.878084 View
ENSG00000122566 HNRNPA2B1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.877966 View
ENSG00000143093 STRIP1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.877878 View
ENSG00000151090 THRB ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.877705 View
ENSG00000108587 GOSR1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.877095 View
ENSG00000116288 PARK7 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.876489 View
ENSG00000111859 NEDD9 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.876472 View
ENSG00000100142 POLR2F ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.876104 View
ENSG00000100351 GRAP2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.875936 View
ENSG00000049759 NEDD4L ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.875344 View
ENSG00000162434 JAK1 ENSG00000198258 UBL5 H. sapiens SSL Slorth 0.87534 View
ENSG00000155111 CDK19 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.875144 View
ENSG00000125450 NUP85 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.874936 View
ENSG00000103769 RAB11A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.87482 View
ENSG00000095951 HIVEP1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.874656 View
ENSG00000159216 RUNX1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.874182 View
ENSG00000160293 VAV2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.874148 View
ENSG00000103653 CSK ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.874056 View
ENSG00000148229 POLE3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.873517 View
ENSG00000136937 NCBP1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.873339 View
ENSG00000162434 JAK1 ENSG00000164022 AIMP1 H. sapiens SSL Slorth 0.873204 View
ENSG00000070061 IKBKAP ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.873188 View
ENSG00000162434 JAK1 ENSG00000248333 CDK11B H. sapiens SSL Slorth 0.873112 View
ENSG00000123358 NR4A1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.872492 View
ENSG00000126216 TUBGCP3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.87223 View