NEDD4L - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NEDD4L	ENSG00000049759	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding potassium channel regulator activity sodium channel regulator activity potassium channel inhibitor activity sodium channel inhibitor activity ion channel binding	RSP5 (S. cerevisiae) Nedd4 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)