JAK1

ENSG00000162434 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005131 growth hormone receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019903 protein phosphatase binding
GO:0031625 ubiquitin protein ligase binding
GO:0031730 CCR5 chemokine receptor binding
GO:0046872 metal ion binding

Drugs

Drug name Description
RUXOLITINIB Tyrosine-protein kinase JAK2 inhibitor
TOFACITINIB Janus Kinase (JAK) inhibitor

Diseases

Disease Name
ALL

Orthologs

Gene Organism
hop D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000054116 TRAPPC3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.895259 View
ENSG00000162434 JAK1 ENSG00000171824 EXOSC10 H. sapiens SSL Slorth 0.895239 View
ENSG00000162434 JAK1 ENSG00000179218 CALR H. sapiens SSL Slorth 0.89503 View
ENSG00000162434 JAK1 ENSG00000187741 FANCA H. sapiens SSL Slorth 0.894642 View
ENSG00000105402 NAPA ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.894566 View
ENSG00000085733 CTTN ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.894551 View
ENSG00000092820 EZR ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.894226 View
ENSG00000162434 JAK1 ENSG00000163466 ARPC2 H. sapiens SSL Slorth 0.894025 View
ENSG00000162434 JAK1 ENSG00000163558 PRKCI H. sapiens SSL Slorth 0.893852 View
ENSG00000118689 FOXO3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.893697 View
ENSG00000035928 RFC1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.893695 View
ENSG00000162434 JAK1 ENSG00000164104 HMGB2 H. sapiens SSL Slorth 0.893623 View
ENSG00000162434 JAK1 ENSG00000196628 TCF4 H. sapiens SSL Slorth 0.893431 View
ENSG00000003400 CASP10 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.893424 View
ENSG00000017797 RALBP1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.892843 View
ENSG00000122512 PMS2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.892699 View
ENSG00000004487 KDM1A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.892576 View
ENSG00000125107 CNOT1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.892406 View
ENSG00000106211 HSPB1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.892332 View
ENSG00000147416 ATP6V1B2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.892213 View
ENSG00000065548 ZC3H15 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.891969 View
ENSG00000122565 CBX3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.891495 View
ENSG00000048052 HDAC9 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.891468 View
ENSG00000143256 PFDN2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.89131 View
ENSG00000137309 HMGA1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.891269 View
ENSG00000068078 FGFR3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.890972 View
ENSG00000112640 PPP2R5D ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.890933 View
ENSG00000129083 COPB1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.890893 View
ENSG00000084774 CAD ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.890888 View
ENSG00000072310 SREBF1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.890618 View
ENSG00000131508 UBE2D2 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.890559 View
ENSG00000131747 TOP2A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.890425 View
ENSG00000083520 DIS3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.890306 View
ENSG00000141552 ANAPC11 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.890075 View
ENSG00000134440 NARS ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.889745 View
ENSG00000089154 GCN1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.889727 View
ENSG00000101199 ARFGAP1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.889566 View
ENSG00000085840 ORC1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.889064 View
ENSG00000019995 ZRANB1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.888999 View
ENSG00000109458 GAB1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.888953 View