PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000120438 TCP1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.888272 View
ENSG00000143799 PARP1 ENSG00000144852 NR1I2 H. sapiens SSL Slorth 0.888126 View
ENSG00000143799 PARP1 ENSG00000175592 FOSL1 H. sapiens SSL Slorth 0.887513 View
ENSG00000100906 NFKBIA ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.88744 View
ENSG00000143799 PARP1 ENSG00000147130 ZMYM3 H. sapiens SSL Slorth 0.887051 View
ENSG00000143799 PARP1 ENSG00000164109 MAD2L1 H. sapiens SSL Slorth 0.886671 View
ENSG00000143799 PARP1 ENSG00000204120 GIGYF2 H. sapiens SSL Slorth 0.885904 View
ENSG00000017797 RALBP1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.885817 View
ENSG00000143799 PARP1 ENSG00000153234 NR4A2 H. sapiens SSL Slorth 0.885685 View
ENSG00000143799 PARP1 ENSG00000185513 L3MBTL1 H. sapiens SSL Slorth 0.88563 View
ENSG00000076555 ACACB ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.885589 View
ENSG00000143799 PARP1 ENSG00000157540 DYRK1A H. sapiens SSL Slorth 0.885441 View
ENSG00000143799 PARP1 ENSG00000179041 RRS1 H. sapiens SSL Slorth 0.885166 View
ENSG00000143799 PARP1 ENSG00000154174 TOMM70 H. sapiens SSL Slorth 0.884564 View
ENSG00000143799 PARP1 ENSG00000170855 TRIAP1 H. sapiens SSL Slorth 0.884414 View
ENSG00000087095 NLK ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.884365 View
ENSG00000143799 PARP1 ENSG00000166913 YWHAB H. sapiens SSL Slorth 0.884194 View
ENSG00000143799 PARP1 ENSG00000164867 NOS3 H. sapiens SSL Slorth 0.884073 View
ENSG00000143799 PARP1 ENSG00000157554 ERG H. sapiens SSL Slorth 0.884043 View
ENSG00000143799 PARP1 ENSG00000163482 STK36 H. sapiens SSL Slorth 0.88343 View
ENSG00000143799 PARP1 ENSG00000183431 SF3A3 H. sapiens SSL Slorth 0.883324 View
ENSG00000143799 PARP1 ENSG00000198258 UBL5 H. sapiens SSL Slorth 0.883275 View
ENSG00000138069 RAB1A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.883173 View
ENSG00000143799 PARP1 ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.883049 View
ENSG00000143799 PARP1 ENSG00000163960 UBXN7 H. sapiens SSL Slorth 0.882955 View
ENSG00000143799 PARP1 ENSG00000215114 UBXN2B H. sapiens SSL Slorth 0.882385 View
ENSG00000143799 PARP1 ENSG00000169252 ADRB2 H. sapiens SSL Slorth 0.881977 View
ENSG00000088986 DYNLL1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.881771 View
ENSG00000143799 PARP1 ENSG00000145495 MARCH6 H. sapiens SSL Slorth 0.881698 View
ENSG00000106245 BUD31 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.881647 View
ENSG00000035403 VCL ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.881602 View
ENSG00000138814 PPP3CA ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.881564 View
ENSG00000110107 PRPF19 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.881542 View
ENSG00000143799 PARP1 ENSG00000204301 NOTCH4 H. sapiens SSL Slorth 0.881214 View
ENSG00000143799 PARP1 ENSG00000163166 IWS1 H. sapiens SSL Slorth 0.881082 View
ENSG00000143799 PARP1 ENSG00000166595 FAM96B H. sapiens SSL Slorth 0.881067 View
ENSG00000143799 PARP1 ENSG00000169251 NMD3 H. sapiens SSL Slorth 0.880552 View
ENSG00000143799 PARP1 ENSG00000164305 CASP3 H. sapiens SSL Slorth 0.880469 View
ENSG00000068024 HDAC4 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.880038 View
ENSG00000143799 PARP1 ENSG00000198909 MAP3K3 H. sapiens SSL Slorth 0.878883 View