PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000161057 PSMC2 H. sapiens SDL Slorth 0.90346 View
ENSG00000111424 VDR ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.903378 View
ENSG00000143799 PARP1 ENSG00000174672 BRSK2 H. sapiens SSL Slorth 0.903345 View
ENSG00000143799 PARP1 ENSG00000170312 CDK1 H. sapiens SDL Slorth 0.903279 View
ENSG00000142534 RPS11 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.90327 View
ENSG00000143799 PARP1 ENSG00000167460 TPM4 H. sapiens SSL Slorth 0.902858 View
ENSG00000143153 ATP1B1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000117143 UAP1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000137285 TUBB2B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000085563 ABCB1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000141279 NPEPPS ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000123983 ACSL3 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000123338 NCKAP1L ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000018625 ATP1A2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000071626 DAZAP1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000141127 PRPSAP2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000139514 SLC7A1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000132463 GRSF1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000074054 CLASP1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000138413 IDH1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000124067 SLC12A4 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000082153 BZW1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000091483 FH ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000090776 EFNB1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000065833 ME1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000135924 DNAJB2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000105281 SLC1A5 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902831 View
ENSG00000002016 RAD52 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.902462 View
ENSG00000123358 NR4A1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902364 View
ENSG00000143799 PARP1 ENSG00000163902 RPN1 H. sapiens SDL Slorth 0.902293 View
ENSG00000143799 PARP1 ENSG00000162961 DPY30 H. sapiens SSL Slorth 0.902282 View
ENSG00000143799 PARP1 ENSG00000182179 UBA7 H. sapiens SDL Slorth 0.902205 View
ENSG00000143799 PARP1 ENSG00000175104 TRAF6 H. sapiens SSL Slorth 0.902077 View
ENSG00000143799 PARP1 ENSG00000180098 TRNAU1AP H. sapiens SSL Slorth 0.90203 View
ENSG00000001167 NFYA ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.902012 View
ENSG00000047315 POLR2B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.901962 View
ENSG00000143799 PARP1 ENSG00000154473 BUB3 H. sapiens SSL Slorth 0.901717 View
ENSG00000108883 EFTUD2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.901714 View
ENSG00000143799 PARP1 ENSG00000205250 E2F4 H. sapiens SSL Slorth 0.901652 View
ENSG00000107758 PPP3CB ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.90157 View