PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000204843 DCTN1 H. sapiens SSL Slorth 0.867009 View
ENSG00000143799 PARP1 ENSG00000150995 ITPR1 H. sapiens SSL Slorth 0.866963 View
ENSG00000143799 PARP1 ENSG00000188739 RBM34 H. sapiens SSL Slorth 0.866777 View
ENSG00000112658 SRF ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.866105 View
ENSG00000143799 PARP1 ENSG00000196284 SUPT3H H. sapiens SSL Slorth 0.86588 View
ENSG00000143799 PARP1 ENSG00000148835 TAF5 H. sapiens SSL Slorth 0.86582 View
ENSG00000139197 PEX5 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.86525 View
ENSG00000101161 PRPF6 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.865027 View
ENSG00000143799 PARP1 ENSG00000169679 BUB1 H. sapiens SSL Slorth 0.864526 View
ENSG00000143799 PARP1 ENSG00000163918 RFC4 H. sapiens SSL Slorth 0.864043 View
ENSG00000143799 PARP1 ENSG00000196923 PDLIM7 H. sapiens SSL Slorth 0.863889 View
ENSG00000143799 PARP1 ENSG00000196924 FLNA H. sapiens SSL Slorth 0.862724 View
ENSG00000143799 PARP1 ENSG00000169439 SDC2 H. sapiens SSL Slorth 0.862693 View
ENSG00000143799 PARP1 ENSG00000167461 RAB8A H. sapiens SSL Slorth 0.862662 View
ENSG00000013503 POLR3B ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.86248 View
ENSG00000143799 PARP1 ENSG00000198554 WDHD1 H. sapiens SSL Slorth 0.862304 View
ENSG00000143799 PARP1 ENSG00000157087 ATP2B2 H. sapiens SSL Slorth 0.862176 View
ENSG00000143799 PARP1 ENSG00000179776 CDH5 H. sapiens SSL Slorth 0.860778 View
ENSG00000076242 MLH1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.860535 View
ENSG00000143799 PARP1 ENSG00000154582 TCEB1 H. sapiens SSL Slorth 0.860493 View
ENSG00000143799 PARP1 ENSG00000178028 DMAP1 H. sapiens SSL Slorth 0.860446 View
ENSG00000143799 PARP1 ENSG00000164402 SEPT8 H. sapiens SSL Slorth 0.860139 View
ENSG00000143799 PARP1 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.86 View
ENSG00000143799 PARP1 ENSG00000178896 EXOSC4 H. sapiens SSL Slorth 0.859923 View
ENSG00000095951 HIVEP1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.859861 View
ENSG00000068078 FGFR3 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.859645 View
ENSG00000092820 EZR ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.85961 View
ENSG00000143799 PARP1 ENSG00000162236 STX5 H. sapiens SSL Slorth 0.859376 View
ENSG00000143799 PARP1 ENSG00000148484 RSU1 H. sapiens SSL Slorth 0.859171 View
ENSG00000065427 KARS ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.858669 View
ENSG00000143799 PARP1 ENSG00000150093 ITGB1 H. sapiens SSL Slorth 0.858633 View
ENSG00000143799 PARP1 ENSG00000198626 RYR2 H. sapiens SSL Slorth 0.857713 View
ENSG00000115464 USP34 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.857361 View
ENSG00000135829 DHX9 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.856517 View
ENSG00000143799 PARP1 ENSG00000182149 IST1 H. sapiens SSL Slorth 0.856048 View
ENSG00000143799 PARP1 ENSG00000178252 WDR6 H. sapiens SSL Slorth 0.855941 View
ENSG00000143799 PARP1 ENSG00000158711 ELK4 H. sapiens SSL Slorth 0.855551 View
ENSG00000143799 PARP1 ENSG00000204231 RXRB H. sapiens SSL Slorth 0.855313 View
ENSG00000143799 PARP1 ENSG00000171132 PRKCE H. sapiens SSL Slorth 0.854721 View
ENSG00000143799 PARP1 ENSG00000184787 UBE2G2 H. sapiens SSL Slorth 0.854142 View