PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000116478 HDAC1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.913282 View
ENSG00000117133 RPF1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.91323 View
ENSG00000143799 PARP1 ENSG00000166598 HSP90B1 H. sapiens SDL Slorth 0.913096 View
ENSG00000138795 LEF1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.912965 View
ENSG00000092847 AGO1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.912942 View
ENSG00000087191 PSMC5 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.912892 View
ENSG00000070831 CDC42 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.912886 View
ENSG00000143799 PARP1 ENSG00000164190 NIPBL H. sapiens SSL Slorth 0.912819 View
ENSG00000143799 PARP1 ENSG00000244687 UBE2V1 H. sapiens SDL Slorth 0.912781 View
ENSG00000143799 PARP1 ENSG00000174775 HRAS H. sapiens SDL Slorth 0.912761 View
ENSG00000143799 PARP1 ENSG00000157554 ERG H. sapiens SDL Slorth 0.912752 View
ENSG00000130985 UBA1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.912725 View
ENSG00000143799 PARP1 ENSG00000197579 TOPORS H. sapiens SSL Slorth 0.912684 View
ENSG00000143799 PARP1 ENSG00000145907 G3BP1 H. sapiens SDL Slorth 0.912647 View
ENSG00000143799 PARP1 ENSG00000167460 TPM4 H. sapiens SDL Slorth 0.912632 View
ENSG00000142541 RPL13A ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.912623 View
ENSG00000072501 SMC1A ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.912584 View
ENSG00000143799 PARP1 ENSG00000170473 PYM1 H. sapiens SSL Slorth 0.912542 View
ENSG00000136504 KAT7 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.912393 View
ENSG00000104365 IKBKB ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.912245 View
ENSG00000143799 PARP1 ENSG00000145386 CCNA2 H. sapiens SDL Slorth 0.912135 View
ENSG00000115355 CCDC88A ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.912046 View
ENSG00000143799 PARP1 ENSG00000172053 QARS H. sapiens SSL Slorth 0.9119 View
ENSG00000143799 PARP1 ENSG00000175745 NR2F1 H. sapiens SSL Slorth 0.91184 View
ENSG00000134001 EIF2S1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.911823 View
ENSG00000143799 PARP1 ENSG00000143878 RHOB H. sapiens SDL Slorth 0.911817 View
ENSG00000143799 PARP1 ENSG00000178950 GAK H. sapiens SSL Slorth 0.911788 View
ENSG00000143799 PARP1 ENSG00000167004 PDIA3 H. sapiens SDL Slorth 0.911708 View
ENSG00000143799 PARP1 ENSG00000175745 NR2F1 H. sapiens SDL Slorth 0.911633 View
ENSG00000143799 PARP1 ENSG00000155097 ATP6V1C1 H. sapiens SDL Slorth 0.911625 View
ENSG00000143799 PARP1 ENSG00000182541 LIMK2 H. sapiens SDL Slorth 0.911582 View
ENSG00000143799 PARP1 ENSG00000187840 EIF4EBP1 H. sapiens SSL Slorth 0.911529 View
ENSG00000111087 GLI1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.911523 View
ENSG00000143799 PARP1 ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.911352 View
ENSG00000114767 RRP9 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.911052 View
ENSG00000100603 SNW1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.910963 View
ENSG00000143799 PARP1 ENSG00000205981 DNAJC19 H. sapiens SSL Slorth 0.910925 View
ENSG00000143799 PARP1 ENSG00000159733 ZFYVE28 H. sapiens SDL Slorth 0.91085 View
ENSG00000143799 PARP1 ENSG00000144476 ACKR3 H. sapiens SDL Slorth 0.91085 View
ENSG00000143799 PARP1 ENSG00000145860 RNF145 H. sapiens SDL Slorth 0.91085 View