PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000165280 VCP H. sapiens SSL Slorth 0.917888 View
ENSG00000112306 RPS12 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.917854 View
ENSG00000100092 SH3BP1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.917819 View
ENSG00000143799 PARP1 ENSG00000188191 PRKAR1B H. sapiens SDL Slorth 0.917816 View
ENSG00000143799 PARP1 ENSG00000159200 RCAN1 H. sapiens SSL Slorth 0.917776 View
ENSG00000143799 PARP1 ENSG00000163930 BAP1 H. sapiens SSL Slorth 0.917742 View
ENSG00000085511 MAP3K4 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.917607 View
ENSG00000143799 PARP1 ENSG00000198825 INPP5F H. sapiens SDL Slorth 0.917529 View
ENSG00000143799 PARP1 ENSG00000167552 TUBA1A H. sapiens SSL Slorth 0.917458 View
ENSG00000117748 RPA2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.917411 View
ENSG00000143799 PARP1 ENSG00000165699 TSC1 H. sapiens SDL Slorth 0.917377 View
ENSG00000143799 PARP1 ENSG00000149823 VPS51 H. sapiens SSL Slorth 0.917332 View
ENSG00000131400 NAPSA ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.917252 View
ENSG00000051382 PIK3CB ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.917206 View
ENSG00000070756 PABPC1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.917063 View
ENSG00000143799 PARP1 ENSG00000148200 NR6A1 H. sapiens SDL Slorth 0.916912 View
ENSG00000143799 PARP1 ENSG00000213923 CSNK1E H. sapiens SDL Slorth 0.91683 View
ENSG00000143799 PARP1 ENSG00000156709 AIFM1 H. sapiens SDL Slorth 0.916822 View
ENSG00000143799 PARP1 ENSG00000143801 PSEN2 H. sapiens SSL Slorth 0.916793 View
ENSG00000134602 STK26 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.916778 View
ENSG00000143799 PARP1 ENSG00000171723 GPHN H. sapiens SDL Slorth 0.916777 View
ENSG00000143799 PARP1 ENSG00000153071 DAB2 H. sapiens SDL Slorth 0.916616 View
ENSG00000140262 TCF12 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.916607 View
ENSG00000115942 ORC2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.916597 View
ENSG00000143799 PARP1 ENSG00000166925 TSC22D4 H. sapiens SDL Slorth 0.916533 View
ENSG00000143799 PARP1 ENSG00000254505 CHMP4A H. sapiens SDL Slorth 0.916409 View
ENSG00000101266 CSNK2A1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.9164 View
ENSG00000143799 PARP1 ENSG00000148606 POLR3A H. sapiens SSL Slorth 0.916355 View
ENSG00000110713 NUP98 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.916348 View
ENSG00000134086 VHL ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.916231 View
ENSG00000143799 PARP1 ENSG00000185787 MORF4L1 H. sapiens SSL Slorth 0.91615 View
ENSG00000141552 ANAPC11 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.916055 View
ENSG00000143799 PARP1 ENSG00000166794 PPIB H. sapiens SSL Slorth 0.916039 View
ENSG00000143799 PARP1 ENSG00000148341 SH3GLB2 H. sapiens SDL Slorth 0.91603 View
ENSG00000143799 PARP1 ENSG00000147133 TAF1 H. sapiens SDL Slorth 0.915755 View
ENSG00000143799 PARP1 ENSG00000174013 FBXO45 H. sapiens SDL Slorth 0.915693 View
ENSG00000138138 ATAD1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.91563 View
ENSG00000143653 SCCPDH ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.91563 View
ENSG00000143799 PARP1 ENSG00000198517 MAFK H. sapiens SSL Slorth 0.915488 View
ENSG00000079785 DDX1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.915391 View