PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000177565 TBL1XR1 H. sapiens SSL Slorth 0.926121 View
ENSG00000143799 PARP1 ENSG00000163399 ATP1A1 H. sapiens SDL Slorth 0.92611 View
ENSG00000143799 PARP1 ENSG00000187098 MITF H. sapiens SSL Slorth 0.925907 View
ENSG00000143799 PARP1 ENSG00000149187 CELF1 H. sapiens SDL Slorth 0.925901 View
ENSG00000143799 PARP1 ENSG00000213782 DDX47 H. sapiens SDL Slorth 0.925901 View
ENSG00000143799 PARP1 ENSG00000221914 PPP2R2A H. sapiens SDL Slorth 0.92585 View
ENSG00000143799 PARP1 ENSG00000161800 RACGAP1 H. sapiens SDL Slorth 0.925684 View
ENSG00000143799 PARP1 ENSG00000170035 UBE2E3 H. sapiens SSL Slorth 0.925542 View
ENSG00000143799 PARP1 ENSG00000173039 RELA H. sapiens SSL Slorth 0.925483 View
ENSG00000127337 YEATS4 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.925287 View
ENSG00000143799 PARP1 ENSG00000168556 ING2 H. sapiens SSL Slorth 0.925276 View
ENSG00000130177 CDC16 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.925272 View
ENSG00000143799 PARP1 ENSG00000196914 ARHGEF12 H. sapiens SDL Slorth 0.92526 View
ENSG00000136573 BLK ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.925103 View
ENSG00000143799 PARP1 ENSG00000244038 DDOST H. sapiens SSL Slorth 0.925086 View
ENSG00000143799 PARP1 ENSG00000196531 NACA H. sapiens SDL Slorth 0.925053 View
ENSG00000143799 PARP1 ENSG00000164056 SPRY1 H. sapiens SDL Slorth 0.924982 View
ENSG00000143799 PARP1 ENSG00000158290 CUL4B H. sapiens SSL Slorth 0.924949 View
ENSG00000085832 EPS15 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.924923 View
ENSG00000136875 PRPF4 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.924903 View
ENSG00000121879 PIK3CA ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.924851 View
ENSG00000143799 PARP1 ENSG00000188996 HUS1B H. sapiens SDL Slorth 0.92485 View
ENSG00000102010 BMX ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.924637 View
ENSG00000143799 PARP1 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.924623 View
ENSG00000143799 PARP1 ENSG00000173334 TRIB1 H. sapiens SDL Slorth 0.924569 View
ENSG00000143799 PARP1 ENSG00000198258 UBL5 H. sapiens SDL Slorth 0.924431 View
ENSG00000143799 PARP1 ENSG00000184481 FOXO4 H. sapiens SSL Slorth 0.924423 View
ENSG00000143799 PARP1 ENSG00000178607 ERN1 H. sapiens SSL Slorth 0.924418 View
ENSG00000143799 PARP1 ENSG00000177606 JUN H. sapiens SDL Slorth 0.924207 View
ENSG00000143799 PARP1 ENSG00000157873 TNFRSF14 H. sapiens SDL Slorth 0.924142 View
ENSG00000143799 PARP1 ENSG00000163660 CCNL1 H. sapiens SDL Slorth 0.92411 View
ENSG00000143799 PARP1 ENSG00000186153 WWOX H. sapiens SSL Slorth 0.924062 View
ENSG00000143799 PARP1 ENSG00000188021 UBQLN2 H. sapiens SDL Slorth 0.924027 View
ENSG00000035928 RFC1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.923974 View
ENSG00000100387 RBX1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.923974 View
ENSG00000143799 PARP1 ENSG00000163558 PRKCI H. sapiens SSL Slorth 0.923848 View
ENSG00000108840 HDAC5 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.923694 View
ENSG00000104517 UBR5 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.923648 View
ENSG00000143799 PARP1 ENSG00000242173 ARHGDIG H. sapiens SDL Slorth 0.923636 View
ENSG00000130939 UBE4B ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.923578 View