PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000177084 POLE H. sapiens SSL Slorth 0.93172 View
ENSG00000143799 PARP1 ENSG00000152234 ATP5A1 H. sapiens SSL Slorth 0.931704 View
ENSG00000116044 NFE2L2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.931694 View
ENSG00000117222 RBBP5 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.931688 View
ENSG00000143799 PARP1 ENSG00000171824 EXOSC10 H. sapiens SSL Slorth 0.931679 View
ENSG00000106459 NRF1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.931588 View
ENSG00000143799 PARP1 ENSG00000159593 NAE1 H. sapiens SDL Slorth 0.931528 View
ENSG00000143799 PARP1 ENSG00000198677 TTC37 H. sapiens SDL Slorth 0.931328 View
ENSG00000143799 PARP1 ENSG00000147130 ZMYM3 H. sapiens SDL Slorth 0.931196 View
ENSG00000105011 ASF1B ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.931184 View
ENSG00000094880 CDC23 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.931158 View
ENSG00000143799 PARP1 ENSG00000148737 TCF7L2 H. sapiens SSL Slorth 0.93112 View
ENSG00000109320 NFKB1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.931111 View
ENSG00000105656 ELL ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.931075 View
ENSG00000083520 DIS3 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.931071 View
ENSG00000143799 PARP1 ENSG00000170836 PPM1D H. sapiens SDL Slorth 0.930798 View
ENSG00000143799 PARP1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.930793 View
ENSG00000143799 PARP1 ENSG00000172269 DPAGT1 H. sapiens SDL Slorth 0.930721 View
ENSG00000143799 PARP1 ENSG00000151292 CSNK1G3 H. sapiens SDL Slorth 0.930721 View
ENSG00000143799 PARP1 ENSG00000161618 ALDH16A1 H. sapiens SDL Slorth 0.930721 View
ENSG00000143799 PARP1 ENSG00000164070 HSPA4L H. sapiens SDL Slorth 0.930721 View
ENSG00000143799 PARP1 ENSG00000198589 LRBA H. sapiens SDL Slorth 0.930721 View
ENSG00000143799 PARP1 ENSG00000148634 HERC4 H. sapiens SDL Slorth 0.930721 View
ENSG00000143799 PARP1 ENSG00000239900 ADSL H. sapiens SDL Slorth 0.930721 View
ENSG00000143799 PARP1 ENSG00000160746 ANO10 H. sapiens SDL Slorth 0.930721 View
ENSG00000143799 PARP1 ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.930673 View
ENSG00000143799 PARP1 ENSG00000184260 HIST2H2AC H. sapiens SSL Slorth 0.930621 View
ENSG00000125952 MAX ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.930575 View
ENSG00000143799 PARP1 ENSG00000276618 RAD17 H. sapiens SSL Slorth 0.930532 View
ENSG00000143799 PARP1 ENSG00000273841 TAF9 H. sapiens SSL Slorth 0.930516 View
ENSG00000114867 EIF4G1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.930434 View
ENSG00000143799 PARP1 ENSG00000184009 ACTG1 H. sapiens SSL Slorth 0.930396 View
ENSG00000143799 PARP1 ENSG00000225830 ERCC6 H. sapiens SDL Slorth 0.93036 View
ENSG00000143799 PARP1 ENSG00000147140 NONO H. sapiens SSL Slorth 0.930346 View
ENSG00000004487 KDM1A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.930292 View
ENSG00000115738 ID2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.930285 View
ENSG00000126457 PRMT1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.930258 View
ENSG00000143799 PARP1 ENSG00000198947 DMD H. sapiens SDL Slorth 0.930244 View
ENSG00000143799 PARP1 ENSG00000185122 HSF1 H. sapiens SSL Slorth 0.930211 View
ENSG00000143799 PARP1 ENSG00000167258 CDK12 H. sapiens SSL Slorth 0.930156 View