ITK

ENSG00000113263 - H. sapiens

Pathways

Go term Description
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0005102 receptor binding

Drugs

Drug name Description
PAZOPANIB Tyrosine-protein kinase LCK inhibitor

Diseases

Disease Name
peripheral T-cell lymphoma

Orthologs

Gene Organism
Btk29A D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000113263 ITK ENSG00000116473 RAP1A H. sapiens SSL Slorth 0.789621 View
ENSG00000113263 ITK ENSG00000114423 CBLB H. sapiens SSL Slorth 0.789252 View
ENSG00000113263 ITK ENSG00000147010 SH3KBP1 H. sapiens SSL Slorth 0.788812 View
ENSG00000096384 HSP90AB1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.788371 View
ENSG00000113263 ITK ENSG00000167513 CDT1 H. sapiens SSL Slorth 0.787444 View
ENSG00000036257 CUL3 ENSG00000113263 ITK H. sapiens SSL Slorth 0.787355 View
ENSG00000113263 ITK ENSG00000126261 UBA2 H. sapiens SSL Slorth 0.786097 View
ENSG00000006451 RALA ENSG00000113263 ITK H. sapiens SSL Slorth 0.785301 View
ENSG00000113263 ITK ENSG00000134982 APC H. sapiens SSL Slorth 0.784697 View
ENSG00000113263 ITK ENSG00000113712 CSNK1A1 H. sapiens SSL Slorth 0.781034 View
ENSG00000113263 ITK ENSG00000196470 SIAH1 H. sapiens SSL Slorth 0.779931 View
ENSG00000113263 ITK ENSG00000141968 VAV1 H. sapiens SSL Slorth 0.779241 View
ENSG00000113263 ITK ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.778684 View
ENSG00000110092 CCND1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.77767 View
ENSG00000113263 ITK ENSG00000154229 PRKCA H. sapiens SSL Slorth 0.776967 View
ENSG00000100028 SNRPD3 ENSG00000113263 ITK H. sapiens SSL Slorth 0.776542 View
ENSG00000113263 ITK ENSG00000166851 PLK1 H. sapiens SSL Slorth 0.775863 View
ENSG00000113263 ITK ENSG00000151247 EIF4E H. sapiens SSL Slorth 0.775176 View
ENSG00000084774 CAD ENSG00000113263 ITK H. sapiens SSL Slorth 0.774693 View
ENSG00000280548 FBL ENSG00000113263 ITK H. sapiens SSL Slorth 0.771592 View
ENSG00000105810 CDK6 ENSG00000113263 ITK H. sapiens SSL Slorth 0.771365 View
ENSG00000113263 ITK ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.768125 View
ENSG00000111276 CDKN1B ENSG00000113263 ITK H. sapiens SSL Slorth 0.766531 View
ENSG00000113263 ITK ENSG00000141480 ARRB2 H. sapiens SSL Slorth 0.764632 View
ENSG00000113263 ITK ENSG00000204843 DCTN1 H. sapiens SSL Slorth 0.763767 View
ENSG00000113263 ITK ENSG00000143190 POU2F1 H. sapiens SSL Slorth 0.762446 View
ENSG00000113263 ITK ENSG00000121481 RNF2 H. sapiens SSL Slorth 0.759274 View
ENSG00000113263 ITK ENSG00000253729 PRKDC H. sapiens SSL Slorth 0.754633 View
ENSG00000107404 DVL1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.753823 View
ENSG00000113263 ITK ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.752042 View