ITK

ENSG00000113263 - H. sapiens

Pathways

Go term Description
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0005102 receptor binding

Drugs

Drug name Description
PAZOPANIB Tyrosine-protein kinase LCK inhibitor

Diseases

Disease Name
peripheral T-cell lymphoma

Orthologs

Gene Organism
Btk29A D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000110713 NUP98 ENSG00000113263 ITK H. sapiens SSL Slorth 0.882101 View
ENSG00000091831 ESR1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.871872 View
ENSG00000113263 ITK ENSG00000185359 HGS H. sapiens SSL Slorth 0.869569 View
ENSG00000112062 MAPK14 ENSG00000113263 ITK H. sapiens SSL Slorth 0.869153 View
ENSG00000067560 RHOA ENSG00000113263 ITK H. sapiens SSL Slorth 0.869145 View
ENSG00000113263 ITK ENSG00000127445 PIN1 H. sapiens SSL Slorth 0.868667 View
ENSG00000113263 ITK ENSG00000158402 CDC25C H. sapiens SSL Slorth 0.868404 View
ENSG00000104365 IKBKB ENSG00000113263 ITK H. sapiens SSL Slorth 0.867356 View
ENSG00000100644 HIF1A ENSG00000113263 ITK H. sapiens SSL Slorth 0.862146 View
ENSG00000113263 ITK ENSG00000114062 UBE3A H. sapiens SSL Slorth 0.861098 View
ENSG00000113263 ITK ENSG00000118689 FOXO3 H. sapiens SSL Slorth 0.859531 View
ENSG00000113263 ITK ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.85879 View
ENSG00000070010 UFD1L ENSG00000113263 ITK H. sapiens SSL Slorth 0.85849 View
ENSG00000113263 ITK ENSG00000164885 CDK5 H. sapiens SSL Slorth 0.856501 View
ENSG00000113263 ITK ENSG00000166501 PRKCB H. sapiens SSL Slorth 0.85087 View
ENSG00000113263 ITK ENSG00000117676 RPS6KA1 H. sapiens SSL Slorth 0.845624 View
ENSG00000070831 CDC42 ENSG00000113263 ITK H. sapiens SSL Slorth 0.843828 View
ENSG00000096968 JAK2 ENSG00000113263 ITK H. sapiens SSL Slorth 0.84382 View
ENSG00000062822 POLD1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.842243 View
ENSG00000100906 NFKBIA ENSG00000113263 ITK H. sapiens SSL Slorth 0.837805 View
ENSG00000113263 ITK ENSG00000183735 TBK1 H. sapiens SSL Slorth 0.832437 View
ENSG00000113263 ITK ENSG00000176105 YES1 H. sapiens SSL Slorth 0.832125 View
ENSG00000113263 ITK ENSG00000181163 NPM1 H. sapiens SSL Slorth 0.83118 View
ENSG00000113263 ITK ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.828032 View
ENSG00000113263 ITK ENSG00000157764 BRAF H. sapiens SSL Slorth 0.826461 View
ENSG00000113263 ITK ENSG00000174903 RAB1B H. sapiens SSL Slorth 0.821782 View
ENSG00000113263 ITK ENSG00000172531 PPP1CA H. sapiens SSL Slorth 0.819134 View
ENSG00000113263 ITK ENSG00000186716 BCR H. sapiens SSL Slorth 0.817694 View
ENSG00000113263 ITK ENSG00000254087 LYN H. sapiens SSL Slorth 0.813293 View
ENSG00000109320 NFKB1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.813089 View
ENSG00000113263 ITK ENSG00000116044 NFE2L2 H. sapiens SSL Slorth 0.809453 View
ENSG00000078140 UBE2K ENSG00000113263 ITK H. sapiens SSL Slorth 0.809256 View
ENSG00000113263 ITK ENSG00000134086 VHL H. sapiens SSL Slorth 0.807083 View
ENSG00000113263 ITK ENSG00000157404 KIT H. sapiens SSL Slorth 0.805885 View
ENSG00000069869 NEDD4 ENSG00000113263 ITK H. sapiens SSL Slorth 0.805621 View
ENSG00000112592 TBP ENSG00000113263 ITK H. sapiens SSL Slorth 0.803253 View
ENSG00000113263 ITK ENSG00000197442 MAP3K5 H. sapiens SSL Slorth 0.801941 View
ENSG00000101966 XIAP ENSG00000113263 ITK H. sapiens SSL Slorth 0.801435 View
ENSG00000058729 RIOK2 ENSG00000113263 ITK H. sapiens SSL Slorth 0.794722 View
ENSG00000109971 HSPA8 ENSG00000113263 ITK H. sapiens SSL Slorth 0.792635 View