SIR2 - SGS1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)
SGS1	YMR190C	No diseases in record	No drugs in record	DNA binding ATP-dependent 3'-5' DNA helicase activity four-way junction helicase activity ATP binding hydrolase activity nucleotide binding helicase activity catalytic activity nucleic acid binding ATP-dependent helicase activity ATP-dependent DNA helicase activity extracellular matrix structural constituent	BLM (H. sapiens) RECQL (H. sapiens) RECQL5 (H. sapiens) WRN (H. sapiens)