SIR2 - PBS2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)
PBS2	YJL128C	No diseases in record	No drugs in record	nucleotide binding MAP kinase kinase activity MAP-kinase scaffold activity protein serine/threonine kinase activity transferase activity ATP binding protein tyrosine kinase activity kinase activity protein kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity	MAP2K1 (H. sapiens) MAP2K2 (H. sapiens) MAP2K5 (H. sapiens) MAP2K7 (H. sapiens) MAP2K3 (H. sapiens) MAP2K4 (H. sapiens) MAP2K6 (H. sapiens)