SIR2 - FKH1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)
FKH1	YIL131C	No diseases in record	No drugs in record	chromatin binding sequence-specific DNA binding DNA replication origin binding DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding centromeric DNA binding protein binding peptidyl-prolyl cis-trans isomerase activity	FOXR1 (H. sapiens)