NCOA2 - SMAD4

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NCOA2	ENSG00000140396	AML chondrosarcoma rhabdomyosarcoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding chromatin binding transcription coactivator activity histone acetyltransferase activity protein binding transcription factor binding ligand-dependent nuclear receptor binding ligand-dependent nuclear receptor transcription coactivator activity thyroid hormone receptor coactivator activity nuclear hormone receptor binding protein dimerization activity	No GO terms in record
SMAD4	ENSG00000141646	colorectal pancreatic small intestine gastrointestinal polyp	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding chromatin binding protein binding collagen binding transforming growth factor beta receptor, common-partner cytoplasmic mediator activity identical protein binding protein homodimerization activity transcription regulatory region DNA binding metal ion binding protein heterodimerization activity I-SMAD binding R-SMAD binding transcription factor activity, protein binding DNA binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding	Med (D. melanogaster)