RB1 - RET

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RB1	ENSG00000139687	retinoblastoma sarcoma breast small cell lung carcinoma	No drugs in record	core promoter binding RNA polymerase II activating transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding kinase binding ubiquitin protein ligase binding identical protein binding androgen receptor binding phosphoprotein binding	lin-35 (C. elegans) Rbf2 (D. melanogaster)
RET	ENSG00000165731	medullary thyroid papillary thyroid pheochromocytoma NSCLC Spitzoid tumour	CABOZANTINIB LENVATINIB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity receptor activity Ras guanyl-nucleotide exchange factor activity calcium ion binding protein binding ATP binding integrin binding	No GO terms in record