PDGFRB - ITGAV

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
ITGAV	ENSG00000138448	large intestine carcinoma	No drugs in record	virus receptor activity fibronectin binding protease binding voltage-gated calcium channel activity protein binding coreceptor activity metal ion binding transforming growth factor beta binding extracellular matrix binding extracellular matrix protein binding opsonin binding protein kinase C binding fibroblast growth factor binding C-X3-C chemokine binding insulin-like growth factor I binding neuregulin binding	pat-2 (C. elegans) if (D. melanogaster)