EPS15 - PDGFRA

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EPS15	ENSG00000085832	ALL	No drugs in record	calcium ion binding protein binding SH3 domain binding polyubiquitin binding identical protein binding cadherin binding involved in cell-cell adhesion	EDE1 (S. cerevisiae) Eps-15 (D. melanogaster)
PDGFRA	ENSG00000134853	GIST idiopathic hypereosinophilic syndrome paediatric glioblastoma	BECAPLERMIN LENVATINIB NINTEDANIB PAZOPANIB PONATINIB REGORAFENIB SUNITINIB	protein kinase activity transmembrane receptor protein tyrosine kinase activity platelet-derived growth factor alpha-receptor activity vascular endothelial growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity platelet-derived growth factor receptor binding protein binding ATP binding vascular endothelial growth factor binding protein homodimerization activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)