CDC73 - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDC73	ENSG00000134371	parathyroid adenoma multiple ossifying jaw fibroma	No drugs in record	RNA polymerase II core binding protein binding chromatin binding transcription factor activity, TFIIF-class transcription factor binding RNA polymerase II C-terminal domain phosphoserine binding transcription factor activity, RNA polymerase II transcription factor binding molecular_function	CDC73 (S. cerevisiae) hyx (D. melanogaster) CG6220 (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)