UBA2 - PTPN11

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
UBA2	ENSG00000126261	No diseases in record	No drugs in record	protein binding ATP binding enzyme activator activity transcription factor binding SUMO activating enzyme activity metal ion binding protein heterodimerization activity nucleotide binding ligase activity small protein activating enzyme activity ubiquitin activating enzyme binding	UBA2 (S. cerevisiae) uba-2 (C. elegans) Uba2 (D. melanogaster)
PTPN11	ENSG00000179295	JMML AML MDS	No drugs in record	phosphoprotein phosphatase activity protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity SH3/SH2 adaptor activity insulin receptor binding protein binding 1-phosphatidylinositol-3-kinase activity protein domain specific binding receptor tyrosine kinase binding D1 dopamine receptor binding phospholipase binding insulin receptor substrate binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity cell adhesion molecule binding peptide hormone receptor binding	PTP1 (S. cerevisiae) ptp-2 (C. elegans) csw (D. melanogaster)