SPAST - LCK

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SPAST	ENSG00000021574	No diseases in record	No drugs in record	protein binding ATP binding microtubule binding microtubule-severing ATPase activity alpha-tubulin binding beta-tubulin binding	SAP1 (S. cerevisiae) YTA6 (S. cerevisiae)
LCK	ENSG00000182866	T-ALL	DASATINIB PAZOPANIB	glycoprotein binding protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein serine/threonine phosphatase activity protein binding ATP binding protein C-terminus binding kinase activity protein kinase binding protein phosphatase binding SH2 domain binding CD4 receptor binding CD8 receptor binding identical protein binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity ATPase binding	Src64B (D. melanogaster)