CASP8 - SRC

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
SRC	ENSG00000197122	colorectal cancer endometrial carcinoma	BOSUTINIB DASATINIB VANDETANIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity SH3/SH2 adaptor activity protein kinase C binding receptor binding insulin receptor binding integrin binding protein binding ATP binding protein C-terminus binding kinase activity enzyme binding kinase binding heme binding estrogen receptor binding SH2 domain binding ion channel binding ephrin receptor binding phosphoprotein binding hormone receptor binding growth factor receptor binding scaffold protein binding cadherin binding involved in cell-cell adhesion	Src64B (D. melanogaster)