HDAC1 - PLCG1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HDAC1	ENSG00000116478	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	transcription regulatory region sequence-specific DNA binding core promoter binding RNA polymerase II transcription factor binding RNA polymerase II repressing transcription factor binding RNA polymerase II transcription corepressor activity transcription factor activity, sequence-specific DNA binding histone deacetylase activity protein binding transcription factor binding deacetylase activity enzyme binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity activating transcription factor binding histone deacetylase binding transcription regulatory region DNA binding protein N-terminus binding NF-kappaB binding repressing transcription factor binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	RPD3 (S. cerevisiae) hda-1 (C. elegans) hda-3 (C. elegans)
PLCG1	ENSG00000124181	angiosarcoma	No drugs in record	phosphatidylinositol phospholipase C activity phospholipase C activity signal transducer activity, downstream of receptor neurotrophin TRKA receptor binding calcium ion binding protein binding protein kinase binding receptor tyrosine kinase binding glutamate receptor binding	PLC1 (S. cerevisiae) plc-3 (C. elegans) sl (D. melanogaster)