MSH6 - RET

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MSH6	ENSG00000116062	colorectal endometrial ovarian	No drugs in record	chromatin binding protein binding mismatched DNA binding methylated histone binding protein homodimerization activity magnesium ion binding four-way junction DNA binding double-stranded DNA binding ATP binding ATPase activity guanine/thymine mispair binding single guanine insertion binding single thymine insertion binding oxidized purine DNA binding MutLalpha complex binding ADP binding DNA binding nucleotide binding single base insertion or deletion binding damaged DNA binding	MSH6 (S. cerevisiae) msh-6 (C. elegans) Msh6 (D. melanogaster)
RET	ENSG00000165731	medullary thyroid papillary thyroid pheochromocytoma NSCLC Spitzoid tumour	CABOZANTINIB LENVATINIB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity receptor activity Ras guanyl-nucleotide exchange factor activity calcium ion binding protein binding ATP binding integrin binding	No GO terms in record