APEX1 - EGLN3

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
APEX1	ENSG00000100823	No diseases in record	No drugs in record	DNA binding damaged DNA binding double-stranded telomeric DNA binding transcription coactivator activity transcription corepressor activity DNA-(apurinic or apyrimidinic site) lyase activity endonuclease activity endodeoxyribonuclease activity RNA-DNA hybrid ribonuclease activity phosphodiesterase I activity uracil DNA N-glycosylase activity protein binding phosphoric diester hydrolase activity double-stranded DNA exodeoxyribonuclease activity double-stranded DNA 3'-5' exodeoxyribonuclease activity 3'-5' exonuclease activity oxidoreductase activity site-specific endodeoxyribonuclease activity, specific for altered base chromatin DNA binding protein complex binding metal ion binding NF-kappaB binding	APN2 (S. cerevisiae) exo-3 (C. elegans) Rrp1 (D. melanogaster)
EGLN3	ENSG00000129521	No diseases in record	No drugs in record	iron ion binding protein binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors L-ascorbic acid binding peptidyl-proline 4-dioxygenase activity	egl-9 (C. elegans)