FURIN - KIT

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FURIN	ENSG00000140564	No diseases in record	No drugs in record	protease binding endopeptidase activity serine-type endopeptidase activity serine-type endopeptidase inhibitor activity protein binding peptidase activity peptide binding metal ion binding nerve growth factor binding	KEX2 (S. cerevisiae) Fur2 (D. melanogaster)
KIT	ENSG00000157404	GIST AML TGCT mastocytosis mucosal melanoma epithelioma	CABOZANTINIB DASATINIB IMATINIB LENVATINIB PAZOPANIB PONATINIB REGORAFENIB SORAFENIB SUNITINIB	protease binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity stem cell factor receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding cytokine binding protein homodimerization activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Pvr (D. melanogaster)