JAK3 - SOS1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK3	ENSG00000105639	acute megakaryocytic leukaemia ETP ALL	TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding protein binding ATP binding protein phosphatase binding	hop (D. melanogaster)
SOS1	ENSG00000115904	No diseases in record	No drugs in record	DNA binding guanyl-nucleotide exchange factor activity Ras guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding SH3 domain binding protein heterodimerization activity	CDC25 (S. cerevisiae) Sos (D. melanogaster)