FURIN - NOTCH1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FURIN	ENSG00000140564	No diseases in record	No drugs in record	protease binding endopeptidase activity serine-type endopeptidase activity serine-type endopeptidase inhibitor activity protein binding peptidase activity peptide binding metal ion binding nerve growth factor binding	KEX2 (S. cerevisiae) Fur2 (D. melanogaster)
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)