ABL1 - IL6ST

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)
IL6ST	ENSG00000134352	hepatocellular carcinoma	TOCILIZUMAB	ciliary neurotrophic factor receptor activity interleukin-11 receptor activity ciliary neurotrophic factor receptor binding protein binding growth factor binding interleukin-11 binding protein homodimerization activity interleukin-27 receptor activity interleukin-6 receptor activity leukemia inhibitory factor receptor activity oncostatin-M receptor activity interleukin-6 receptor binding interleukin-6 binding	No GO terms in record