ABL1 - BCL2

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ABL1 ENSG00000097007 CML
ALL
T-ALL
BOSUTINIB
DASATINIB
IMATINIB
NILOTINIB
PONATINIB
REGORAFENIB
magnesium ion binding
DNA binding
actin monomer binding
nicotinate-nucleotide adenylyltransferase activity
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
SH3 domain binding
syntaxin binding
manganese ion binding
actin filament binding
mitogen-activated protein kinase binding
proline-rich region binding
receptor binding
abl-1 (C. elegans)
Abl (D. melanogaster)
BCL2 ENSG00000171791 NHL
CLL

No drugs in record

protease binding
protein binding
transcription factor binding
channel activity
channel inhibitor activity
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
sequence-specific DNA binding
protein heterodimerization activity
BH3 domain binding
protein phosphatase 2A binding

No GO terms in record