CASP8 - XPO1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
XPO1	ENSG00000082898	CLL	No drugs in record	RNA binding nuclear export signal receptor activity transporter activity nucleocytoplasmic transporter activity protein binding Ran GTPase binding protein domain specific binding	CRM1 (S. cerevisiae) xpo-1 (C. elegans) emb (D. melanogaster)