LEF1 - TRAF6

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
LEF1	ENSG00000138795	B-ALL T-ALL eyelid sebaceous carcinoma AML lymphomas	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding beta-catenin binding transcription factor binding DNA binding, bending estrogen receptor activity estrogen receptor binding enhancer binding histone binding histone deacetylase binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process sequence-specific DNA binding transcription regulatory region DNA binding gamma-catenin binding armadillo repeat domain binding C2H2 zinc finger domain binding	pop-1 (C. elegans) pan (D. melanogaster)
TRAF6	ENSG00000175104	No diseases in record	No drugs in record	ubiquitin-protein transferase activity tumor necrosis factor receptor binding protein binding zinc ion binding ligase activity protein kinase binding mitogen-activated protein kinase kinase kinase binding ubiquitin conjugating enzyme binding ubiquitin protein ligase binding thioesterase binding identical protein binding histone deacetylase binding protein kinase B binding protein N-terminus binding ubiquitin protein ligase activity	Traf6 (D. melanogaster)