CASP8 - SMURF1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
SMURF1	ENSG00000198742	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding phospholipid binding activin binding ubiquitin protein ligase activity I-SMAD binding R-SMAD binding	RSP5 (S. cerevisiae)