TERT - MTOR

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TERT	ENSG00000164362	melanoma glioblastoma hepatocellular carcinoma bladder skin basal cell skin squamous cell mesothelioma medulloblastoma other tumour types	No drugs in record	tRNA binding transcription coactivator binding DNA binding telomerase activity telomerase RNA reverse transcriptase activity RNA binding RNA-directed DNA polymerase activity protein binding nucleotidyltransferase activity telomeric DNA binding protein homodimerization activity metal ion binding telomerase RNA binding RNA-directed 5'-3' RNA polymerase activity	EST2 (S. cerevisiae)
MTOR	ENSG00000198793	endometrial carcinoma head and neck clear cell renal cell carcinoma anaplastic thyroid cancer urothelial cell carcinoma central nervous system tumours testicular germ cell tumours and other tumour types	No drugs in record	RNA polymerase III type 1 promoter DNA binding RNA polymerase III type 2 promoter DNA binding RNA polymerase III type 3 promoter DNA binding TFIIIC-class transcription factor binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity protein kinase binding protein domain specific binding ribosome binding phosphoprotein binding ribonucleoprotein complex binding chromatin DNA binding nucleocytoplasmic transporter activity	TOR2 (S. cerevisiae) Tor (D. melanogaster)